Internal Medicine & Patient Care

Biography

Eman H.EL-Adawy has completed his MD from Mansoura University. She is associate professor of Internal Medicine and Endocrinology department in Spescialized Medical Hospital,Faculty of Medicine, Mansoura City, Egypt. She has published more than 10 papers in reputed journals.

Abstract

Background:In Egypt, it seems that adolescent girls are candidate for vitamin D deficiency (VDD), mostly due to inadequate sun exposure as a result of the culture and social dress codes. Curently there is growing evidence that VDD and iron deficiency anemia (IDA) are associated . Aim; investigate the frequency of VDD in adolescent females with IDA and demonstrate whether VD level was correlated with serum iron indices.  Methods: Forty adolescent with IDA and 30 healthy control were compared to determine the degree of VD level; where VDD ( ≤20 ng/mL), VD insufficiency  ( 20-30 ng/Ml) and VD sufficiency ( >30 ng/Ml). BMI, CBC, TIBC, serum ferritin, ionized calcium and 25(OH)D  were measured. Results:  Subnormal VD was more frequent in the IDA group (75%) than control (40%); where 19 adolescent female patients (47.5%) were VD deficient, 11 (27.5%) were insufficient and 10 (25%) were sufficient; in control group VDD was present in 4 (20%), VDI in 4 (20%) and VDS in 12 (60%) respectively. The mean level of VD was significantly lower in winter than summer (16.87 vs. 31.57 mg/dL, P <0.001). Analysis of the factors potentially associated with D levels was performed, including BMI, season and serum iron profile, and we found no significant independent predictors of VD levels. Conclusions. VDD has a high frequency in Egyptian adolescent females with IDA, however it is not significantly correlated with iron indicies. Measurement of VD level in such patients, a procedure that is not currently a part of routine investigation, could be necessary.